• Riris Wahyu Anggraini Poltekkes Kemenkes Malang
  • Lenni Saragih Poltekkes Kemenkes Malang
  • Ni Luh Putu Eka Poltekkes Kemenkes Malang


The acute phase of the burns case is a form of critical trauma with a number of high mortality, Therefore, burn wounds is facing the complexity of problems that need particular attention. Aloe vera contains saponins active substances which are antiseptic and glucomannan as fibroblast growth that can help the healing process. The aim of this research is to examine the Aloe vera extracts toward the healing of burns grade two. The extract is made by maceration using solvent ethanol 70%. This research uses white male wistar rats (Rattus norvergicus)  who were divided into 4 groups that are given extra aloe vera gel concentration 10% aloe vera concentration 20% and the control group Silversulfadiazine1% and NaCl 0.9%. The observed parameters macroscopic picture (color, extent and presence or absence of exudate).All data is processed and analized statistically using SPSS 23. The results of the statistical analysis Paired Samples T-Test  and Independent Samples T-test showed that the average wound area  between NaCl 0,9%, Silver Sulfadiazine 1%, Aloe vera 10%, and Aloe vera 20% has no significant difference. Conclusion of this study is Aloe vera 10% and 20% have the same effect with Silver Sulfadiazine 1% for healing of skin  burns and applied to humans as an alternative treatment of early burns with a relatively cheap price.


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How to Cite
ANGGRAINI, Riris Wahyu; SARAGIH, Lenni; EKA, Ni Luh Putu. TOPICAL EFFECTS OF ALOE VERA VEGETABLES EXTRACT OF 10%, AND 20% CONCENTRATION TOWARD THE CROSSOSCOPIC PICTURE OF FUEL GRADE II IN RATTUS NORVERCICUS RATS WISTAR SHEET. Journal of Applied Nursing (Jurnal Keperawatan Terapan), [S.l.], v. 5, n. 1, p. 53 - 64, mar. 2019. ISSN 2442-6873. Available at: <>. Date accessed: 01 dec. 2022. doi:
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